SUBHAS BHUIN
BANGUR INSTITUTE OF NEUROSCIENCES , IPGMER , KOLKATA, INDIA
Title: PROFILE AND SEVERITY CORRELATION OF ATAXIA PATIENTS IN A TERTIARY CARE INSTITUTE IN EASTERN INDIA
Biography
Biography: SUBHAS BHUIN
Abstract
Introduction - Clinical profile and severity correlation of ataxia patients in our population is still varied . This study is taken up to explore this aspect. Methods - A cross-sectional study was conducted at XXX. Clinical parameters with severity correlation( SARA scale ) in selected patients was determined. Results: In 188 patients , 127 had cerebellar ataxia(SCA 2, 3, 1 ,6 ,12 , MSA C , Wilsons disease) , 42 had sensory ataxia mainly Sensory ataxic GBS, CIDP variant(CISP) , Sjogrens and 19 had Mixed cerebellar sensory ataxia (Multiple sclerosis , Vitamin E deficiency ). Cerebellar ataxias had higher disability at presentation ( mean SARA score- 21.87) than mixed ataxias ( SARA – 19.68). Increase in SARA score was seen more in mixed ataxias (3.64) than cerebellar ( 3.01) . Disability progression is more in MSA C and SCA 2 has lesser degree of progression ( despite highest SARA score- 28.5 at presentation). Conclusion - MSA C, SCA , Multiple sclerosis are majority in respective ataxia groups.. Maximum disability and progression is seen in MSA and SCA (SARA scale) . Chances of early detection and knowledge about progression of ataxia spectrum in our population is attempted.Limitations : Further follow up of the patients with ataxia required to get a clear insight Further Scope : Early diagnosis and management strategies can be validated for better management and prevention of deterioration to make the otherwise debilitating ataxia disorders a preventable one. Conflict of interest- Nil