Dementia

Dementia is a wide category of brain diseases that cause an abiding and often moderate decrease in the capability to think and recall that is acute enough to affect a person's normal functioning. The most usual category of dementia is Alzheimer's disease, which makes up 50% to 70% of cases. The indications of dementia differ across types and stages of the diagnosis. The most usual affected areas are memory, visual-spatial, problem solving, language and attention. There is no known treatment for dementia. Cholinesterase inhibitors such as donepezil are frequently used and may be beneficial in moderate disorder.

Vascular Dementia and Stroke

Vascular dementia is also called multi-infarct dementia (MID) and vascular intellectual impedance. Dementia is a general term describing problems with reasoning, planning, judgment, memory and other thought processes caused by brain damage from impaired blood flow to your brain. People with Dementia give dynamic subjective hindrance, intensely or subacutely as in mellow psychological debilitation, every now and again step-wise, after various cerebrovascular occasions (strokes). According to a neurologist, Dementia is the second-most-common form of dementia after Alzheimer's disease (AD). . The temporal relationship between a stroke and cognitive deficits is needed to make the diagnosis. People with vascular dementia present with progressive cognitive impairment, acutely or sub acutely as in mild cognitive impairment, frequently step-wise, after multiple cerebrovascular events (strokes).

Vascular Cognitive Impairment    

Vascular intellectual disability is a decrease in deduction capacities caused by a malady that harms the mind's veins. The vascular malady may cause intellectual hindrance all alone, and can likewise add to impedances in considering and conduct in a man with another cerebrum illness, for example, Alzheimer’s. Cognitive weakness normally goes with clinical disorders in Alzheimer’s related to the vascular ailment of the mind. In view of developing definitional criteria, the recurrence of subjective weakness inferable from cerebrovascular ailment is hard to decide. Dementia happens in up to 33% of elderly patients with stroke as opposed to an immaculate Dementia disorder.

Amyloid Imaging in Dementia

Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in neuroimaging of Alzheimer's disease patients, associated with amyloid-modifying therapies, particularly human monoclonal antibodies such as aducanumab. There are two types of ARIA - ARIA-E and ARIA-H. The phenomenon was first seen in trials of bapineuzumab.

Alzheimer’s disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and gradually worsens over time. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, and loss of motivation, not managing self-care, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death

Neurodegenerative Diseases

Neuro degeneration is the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases – including amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease – occur as a result of neurodegenerative processes. Such diseases are incurable, resulting in progressive degeneration and/or death of neuron cells. As research progresses, many similarities appear that relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously

Brain Diseases

Central nervous system problems are also known as central nervous system disorders. These are the neurological problems that affect the function and structure of the brain and spinal cord, which form the central nervous system. Signs are like persistent headache; face pain, band and legs pain, inability to concentrate and slurred speech etc.

Ageing and Dementia

Aging is a main risk element for most common neurodegenerative problems, including mild cognitive impairment, dementias including cerebrovascular disease, Alzheimer's disease, Lou Gehrig's disease, and Parkinson's disease. While much research has focused on problems of aging, there are less informative studies on the molecular biology of the aging brain in the lack of neurodegenerative disease or the neuropsychological discription of healthy older adults. However, research suggests that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes.

Dementia Care Management

Dementia care management is nothing but care provided to dementia patients at home/hospital. In-home care includes a wide range of services provided in the home, rather than in a hospital or care facility. It can allow a person with Alzheimer's or other dementia to stay in his or her own home. It also can be of great assistance to caregivers. It can allow a person with Alzheimer's or other dementia to stay in his or her own home.

Dementia Nursing

Dementia nurses can provide treatment, support and care for people with dementia and mental health problems. They might assess you at your home, and they advise you and your careers on ways of improving your health and quality of life. Dementia nurses do not normally carry out physical tasks like changing bandages or keeping saline etc. Dementia nurses will do psychological activities to care dementia patients.

Diagnosis and treating Dementia

Diagnosing dementia and its categories can be challenging. People have dementia when they have analytical impairment and lose their capability to do daily functions, such as driving safely, taking medications, taking food time on time etc. To diagnose the reason of dementia, the physician must recognize the pattern of the dropping of skills, function and understand what a person is still capable to do. Recently, biomarkers are available to make a more exact diagnosis of Alzheimer's problem. Doctor will examine your medical condition, history, symptoms and conduct a physical/mental examination.

Neuropharmacology

Neuropharmacology will give information about how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuro psychopharmacology), including the study of how drug dependence and addiction affect the human brain.  Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function.

Novel therapeutics for Dementia:

Novel Therapeutic Technology is a leading pioneer in the development of sophisticated and practical drug delivery systems. NTT's Ethosome technology provides the means to significantly enhance drug penetration of topical delivery applications, exponentially increasing therapeutic efficiency. With worldwide recognized drugs combined with NTT know-how, Pharmaceutical companies are able to introduce new and better drugs to the market, thus greatly reducing side effects, improving patient compliance, and increasing the patient’s quality of life.

Neuro Oncology and CNS:

It is a branch of Medical Sciences majorly deals with Neuro tumors. Deals with Studies related to Brain and Spinal cord neoplasms. Neuro-oncology and Pediatric Neuro-oncology are the two different Concepts that differentiate the determining methodology of Neuro tumors. Neuro-oncology mainly includes especially related topics like Radiation therapy, Neurosurgery, Neuroimaging, social, Psychological, Neuropathology and psychiatric aspects.

Related Conferences: 14th International Conference on Alzheimers Disease & Dementia October 12-13, 2020 Zurich, Switzerland, Vascular Dementia and Neurodegenerative Diseases, May 18-19, 2020 Osaka, Japan, 13th International Conference onDementia and Vascular Dementia June 24-25, 2020 Zurich, Switzerland, 12th International Conference on Vascular Dementia June 22-23, 2020 Prague, Czech Republic, Dementia, Alzheimers and Neurological Disorders May 07-08, 2020 Zagreb, Croatia,16th International Conference and Exhibition on Alzheimers Disease, Dementia & Ageing April 13-14, 2020, London, UK.

Related Societies and Associations: Alzheimer’s Society, Dementia Society of America, Alzheimer's Association, Dementia Australia, Alzheimer's Disease International, Alzheimer Society of Ireland, Alzheimer Society of Toronto, American Stroke Association, Alzheimer's Research UK, Social care institute for excellence, Fraser Health, Calderdale Council.

The global market for treatments of syndromes like dementia and movement disorders was valued at 10.5 billion in 2011 and was estimated to reach $11.1 billion in 2012. Total market value is expected to reach $16.7 billion in 2017 after increasing at a five-year compound annual growth rate (CAGR) of 8.5%.

Someone in the world develops dementia every 3 seconds. There were an estimated 46.8 million people worldwide living with dementia in 2015 and this number is believed to be close to 50 million people in 2017. These numbers will almost double every 20 years, reaching 75 million in 2030 and 131.5 million in 2050. Much of the increase will be in developing countries. Already 58% of people with dementia live in low and middle income countries, but by 2050 this will rise to 68%. The fastest growth in the elderly population is taking place in China, India, and their south Asian and western Pacific neighbours.

Major Neuroscience Societies and Associations in Singapore:

Major Dementia and Alzheimer’s Societies and Associations around Globe:

Top Neuroscience Universities in Singapore:

Top Neuroscience Universities in Globe:

Hospital Associated with Dementia:

Companies Associated with Dementia in Singapore

Top Dementia Companies:

References:

• http://www.alzheimers.org.uk/dementiauk
• https://en.wikipedia.org/wiki/Alzheimer's_Research_UK
• http://www.alzheimersresearchuk.org/
• http://www.alz.org/uk/dementia-alzheimers-uk.asp
• http://www.alzheimersresearchuk.org/about-dementia/facts-stats/
• http://www.alz.org/research/funding/alzheimers_our_commitment.asp
• https://www.ucl.ac.uk/dementia
• http://www.city.ac.uk/courses/cpd/evidence-based-dementia-care
• http://www.kcl.ac.uk/ioppn/depts/oldage/research/bdr.aspx